O’Brien is hosting the Oscars for the first time tonight as he leads proceedings for the 2025 Academy Awards.
While his opening monologue fired shots at Karla Sofia Gascon and her offensive tweets and made jokes about every Best Picture nominee.
A bizarre opening skit from O'Brien, which was controversial (ITV)
What freaked fans out in particular though was his opening skit, which saw him break out of Demi Moore’s body in the style of The Substance.
This led to major reactions from fans, with one saying: “Yeah soooo this opening substance monologue is actually offensive but ok #Oscars2025.”
A second replied to a video of the skit saying: "Bad taste".
Another jokingly said: “Please, this stupid man”.
One viewer tweeted: "the oscars did not need to introduce conan that way."
This was not unanimous though, as some found the opening skit fun and enjoyable.
One fan tweeted: "Conan doing the substance… it’s so wild and fun having an oscars host who actually watches the movies."
Another said: "That The Substance opening was funny! I'm having fun!"
O'Brien's opening skit and monologue went on to feature a moment with Adam Sandler which has since gone viral, in which he chastises the comedic actor for coming in his typical baggy hoodie and shorts look.
The actor went up and joked around with Best Actor nominated Timothee Chalamet, yelling 'Chalamet!' in his face.
Timothee Chalamet and Adam Sandler (ITV)
O'Brien's shot at Gascon saw him saying: "Little fact for you, Anora uses the F word 479 times. That's three more than the record set by Karla Sofia Gascon's publicist."
Gascon's racist tweets resurfaced after becoming the first ever openly Trans actress to be nominated for an Oscar acting role.
The actor ended up attending The Oscars tonight and smiled along as O'Brien poked fun at her.
She spoke to The Hollywood Reporter after it was announced that she would be attending, as she skipped the red carpet.
She said: "I’m not sure how I feel, but I’m grateful to be back.
"I’m grateful to all those who’ve believed in me — to Netflix, the production company and my colleagues.
"We can close this beautiful and difficult path that began three years ago.”
She also gave an apology in a televised interview, saying: "I want to acknowledge the conversation around my past social media posts that have caused hurt.
"As someone in a marginalized community, I know this suffering all too well and I am deeply sorry to those I have caused pain. All my life I have fought for a better world. I believe light will always triumph over darkness.”
